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Table 1 Bacterial strains used in this study

From: Salmonella enterica serovar Typhi genomic regions involved in low pH resistance and in invasion and replication in human macrophages

Bacterial strains Relevant characteristics Reference
S. Typhi IMSS-1 Salmonella enterica serovar Typhi Vi serotype. Mexican clinical reference strain. Puente et al. (1987)
S. Typhi IMSS-1 ΔleuO::kmr S. Typhi containing a deletion of the LysR-type regulator LeuO Hernández-Lucas et al. (2008)
S. Typhi IMSS-1 ΔSTY0159 S. Typhi containing a deletion of the LysR-type regulator STY0159 This study
S. Typhi IMSS-1 ΔSTY0277 S. Typhi containing a deletion of the LysR-type regulator STY0277 This study
S. Typhi IMSS-1 ΔSTY0341 S. Typhi containing a deletion of the LysR-type regulator STY0341 This study
S. Typhi IMSS-1 ΔSTY0651 S. Typhi containing a deletion of the LysR-type regulator STY0651 This study
S. Typhi IMSS-1 ΔSTY0730 S. Typhi containing a deletion of the LysR-type regulator STY0730 This study
S. Typhi IMSS-1 ΔSTY1693 S. Typhi containing a deletion of the LysR-type regulator STY1693 This study
S. Typhi IMSS-1 ΔSTY2510 S. Typhi containing a deletion of the LysR-type regulator STY2510 This study
S. Typhi IMSS-1 ΔSTY2660 S. Typhi containing a deletion of the LysR-type regulator STY2660 This study
S. Typhi IMSS-1 ΔSTY2821 S. Typhi containing a deletion of the LysR-type regulator STY2821 This study
S. Typhi IMSS-1 ΔSTY3158 S. Typhi containing a deletion of the LysR-type regulator STY3158 This study
S. Typhi IMSS-1 ΔSTY3293 S. Typhi containing a deletion of the LysR-type regulator STY3293 This study
S. Typhi IMSS-1 ΔSTY3415 S. Typhi containing a deletion of the LysR-type regulator STY3415 This study
S. Typhi IMSS-1 ΔSTY3547 S. Typhi containing a deletion of the LysR-type regulator STY3547 This study
S. Typhi IMSS-1 ΔSTY4196 S. Typhi containing a deletion of the LysR-type regulator STY4196 This study
S. Typhi IMSS-1 ΔSTY4468 S. Typhi containing a deletion of the LysR-type regulator STY4468 This study
S. Typhi IMSS-1 ΔltrR S. Typhi containing a deletion of the LysR-type regulator LtrR Villareal et al. (2014)
S. Typhi IMSS-1 ΔltrRompA::kmr S. Typhi containing two deletions, one of them correspond to the LysR-type regulator LtrR and the second deletion correspond to the OmpA outer membrane protein This study
S. Typhi IMSS-1 ΔltrRompR::kmr S. Typhi containing two deletions, one of them correspond to the LysR-type regulator LtrR and the second deletion correspond to the regulator OmpR This study
S. Typhi IMSS-1 ΔpmrAB::kmr S. Typhi containing a deletion in the two component system PmrAB Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 ΔphoP::kmr S. Typhi containing a deletion in the two component system PhoP Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 ΔnarP::kmr S. Typhi containing a deletion in the two component system NarP This study
S. Typhi IMSS-1 ΔsoxRS::kmr S. Typhi containing a deletion in the two component system SoxRS This study
S. Typhi IMSS-1 ΔarcA S. Typhi containing a deletion in the two component system ArcA This study
S. Typhi IMSS-1 ΔcpxRA::kmr S. Typhi containing a deletion in the two component system CpxRA Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 ΔssrB::kmr S. Typhi containing a deletion in the two component system SsrB Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 Δfis::kmr S. Typhi containing a deletion in the nucleoid-associated protein FIS This study
S. Typhi IMSS-1 ΔSTYhns99::kmr S. Typhi containing a deletion in the nucleoid-associated protein HNS Flores-Valdez et al. (2003)
S. Typhi IMSS-1 Δlrp::kmr S. Typhi containing a deletion in the nucleoid-associated protein LRP Medina-Aparicio et al. (2011)
S. Typhi IMSS-1 Δlrphns::kmr S. Typhi containing two deletions, one of them correspond to the nucleoid-associated protein LRP and the second deletion correspond to the nucleoid-associated protein HNS Medina-Aparicio et al. (2011)
S. Typhi IMSS-1 ΔihfA::kmr S. Typhi containing a deletion in the nucleoid-associated protein IHFA Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 ΔmalT S. Typhi containing a deletion in the LuxR-like MalT protein This study
S. Typhi IMSS-1 ΔsdiA S. Typhi containing a deletion in the LuxR-like SdiA protein This study
S. Typhi IMSS-1 ΔluxS::kmr S. Typhi containing a deletion in the LuxR-like LuxS protein This study
S. Typhi IMSS-1 Δfur::kmr S. Typhi containing a deletion in the FuR-like FUR protein This study
S. Typhi IMSS-1 Δcrp S. Typhi containing a deletion in the CRP-like CRP protein Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 Δfnr::kmr S. Typhi containing a deletion in the CRP-FNR-like FNR protein Medina-Aparicio et al. (2017)
S. Typhi IMSS-1 ΔompR S. Typhi containing a deletion in the OmpR regulator Villareal et al. (2014)
S. Typhi IMSS-1 ΔSTY0123-STY0125::kmr S. Typhi containing a deletion in the thiQP-tpbA genes This study
S. Typhi IMSS-1 ΔF1::kmr Deleted from base 5114 to base 11,245 (6.131 kb, STY0005-STY0011). This study
S. Typhi IMSS-1 ΔF2::kmr Deleted from base 15,020 to 44,181 (29.161 kb, STY0014-STY0045). This study
S. Typhi IMSS-1 ΔF3::kmr Deleted from base 56,686 to base 104,274 (47.588 kb, STY0056-STY0106). This study
S. Typhi IMSS-1 ΔF4::kmr Deleted from base 115,571 to base 140,755 (25.184 kb, STY0114-STY0138). This study
S. Typhi IMSS-1 ΔF14::kmr Deleted from base 2,493,002 to base 2,499,616 (6.614 kb, STY2655-STY2662). This study
S. Typhi IMSS-1 ΔF16::kmr Deleted from base 2,445,015 to base 2,460,717 (15.702 kb, STY2610-STY2625). This study
S. Typhi IMSS-1 ΔF17::kmr Deleted from base 2,436,294 to base 2,443,543 (7.249 kb, STY2600-STY2608). This study
S. Typhi IMSS-1 ΔF18::kmr Deleted from base 2,400,919 to base 2,433,642 (32.723 kb, STY2564-STY2596). This study
S. Typhi IMSS-1 ΔF19::kmr Deleted from base 2,342,588 to base 2,400,843 (58.255 kb, STY2508-STY2563) This study
S. Typhi IMSS-1 ΔF20::kmr Deleted from base 2,311,811 to base 2,331,187 (19.376 kb, STY2483-STY2497) This study
S. Typhi IMSS-1 ΔF22::kmr Deleted from base 2,200,548 to base 2,215,156 (14.608 kb, STY2370-STY2383) This study
S. Typhi IMSS-1 ΔF23::kmr Deleted from base 2,150,560 to base 2 199,512 (48.952 kb, STY2321-STY2368) This study
S. Typhi IMSS-1 ΔF24::kmr Deleted from base 2,101,051 to base 2,150,557 (49.506 kb, STY2276-STY2320) This study
S. Typhi IMSS-1 ΔF25::kmr Deleted from base 2,052,806 to base 2,097,723 (44.917 kb STY2217-STY2271) This study
S. Typhi IMSS-1 ΔF28::kmr Deleted from base 1,936,029 to base 1,954,615 (18.586 kb, STY2083-STY2101) This study
S. Typhi IMSS-1 ΔF29::kmr Deleted from base 1,855,187 to base 1,935,559 (80.372 kb, STY1965-STY2081) This study
S. Typhi IMSS-1 ΔF31::kmr Deleted from base 1,803,420 to base 1,823,145 (19.725 kb, STY1910-STY1929) This study
S. Typhi IMSS-1 ΔF36::kmr Deleted from base 1,701,377 to base 1,712,613 (11.236 kb, STY1779-STY1791) This study
S. Typhi IMSS-1 ΔF37::kmr Deleted from base 1,674,560 to base 1,693,618 (19.058 kb, STY1755-STY1771) This study
S. Typhi IMSS-1 ΔF38::kmr Deleted from base 1,625,241 to base 1,674,133 (48.892 kb, STY1698-STY1754) This study
S. Typhi IMSS-1 ΔF40::kmr Deleted from base 1,581,741 to base 1,601,909 (20.168 kb, STY1653-STY1672) This study
S. Typhi IMSS-1 ΔF41::kmr Deleted from base 1,573,199 to base 1,580,739 (7.540 kb, STY1645-STY1651) This study
S. Typhi IMSS-1 ΔF42::kmr Deleted from base 1,551,982 to base 1,570,836 (18.854 kb, STY1616-STY1639) This study
S. Typhi IMSS-1 ΔF43::kmr Deleted from base 1,511,563 to base 1,551,982 (40.419 kb, STY1562-STY1615) This study
S. Typhi IMSS-1 ΔF44::kmr Deleted from base 1,453,776 to base 1,511,522 (57.746 kb, STY1496-STY1561) This study
S. Typhi IMSS-1 ΔF45::kmr Deleted from base 1,404,648 to base 1,451,382 (46.734 kb, STY1454-STY1493) This study
S. Typhi IMSS-1 ΔF46::kmr Deleted from base 1,359,382 to base 1,403,895 (44.513 kb, STY1409-STY1452) This study
S. Typhi IMSS-1 ΔF47::kmr Deleted from base 1,314,180 to base 1,359,236 (45.056 kb, STY1353-STY1408) This study
S. Typhi IMSS-1 ΔF52::kmr Deleted from base 1,085,337 to base 1,134,126 (48.789 kb, STY1114-STY1170) This study
S. Typhi IMSS-1 ΔF54::kmr Deleted from base 1,017,923 to base 1,058,825 (40.902 kb, STY1024-STY1081) This study
S. Typhi IMSS-1 ΔF55::kmr Deleted from base 1,003,596 to base 1,014,693 (11.097 kb, STY1005-STY1019) This study
S. Typhi IMSS-1 ΔF59::kmr Deleted from base 794,269 to base 849,155 (54.886 kb, STY0797-STY0854) This study
S. Typhi IMSS-1 ΔF64::kmr Deleted from base 606,760 to base 633,465 (26.705 kb, STY0605-STY0631) This study
S. Typhi IMSS-1 ΔF73::kmr Deleted from base 302,488 to base 366,847 (64.359 kb, STY0286-STY0357) This study
S. Typhi IMSS-1 ΔF77::kmr Deleted from base 2,876,422 to base 2,918,810 (42.388 kb, STY3004- STY3052) This study
S. Typhi IMSS-1 ΔF78::kmr Deleted from base 2,921,547 to base 2,960,653 (39.106 kb, STY3057- STY3094) This study
S. Typhi IMSS-1 ΔF95::kmr Deleted from base 3,526,926 to base 3,552,416 (25.490 kb, STY3674- STY3708) This study
S. Typhi IMSS-1 ΔF107::kmr Deleted from base 4,035,317 to base 4,105,650 (70.333 kb, STY4176- STY4239) This study
S. Typhi IMSS-1 ΔF112::kmr Deleted from base 4,367,185 to base 4,408,807 (41.622 kb, STY4481- STY4519) This study
S. Typhi IMSS-1 ΔF114::kmr Deleted from base 4,421,390 to base 4,472,347 (50.957 kb, STY4534- STY4596) This study